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Sintesis Dan Uji Anti Oksidan Senyawa 1,5-bis(3'-etoksi-4'-hidroksifenil)-1,4-pentadien-3-on

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ABSTRACTrnrnrnrn(A) ENJANG RUSNAWAN (2004210051)rnrn(B) SYNTHESIS AND EXAMINATION ANTIOXIDANT OF 1,5-bis(3’-etoxy-4’-hydroxyphenyl)-1,4-pentadiene-3-on rnrn(C) x + 68 pages; 2008; 13 tables; 31 diagrams; 15 attachmentsrnrn(D) Keywords: Antioxidant activity, 1,5-bis(3’-etoxy-4’-hydroxyphenyl)-1,4-pentadiene-3-on, aldol condensation, curcumin. rnrn(E) The yellownish crystal of 1,5-bis(3’-etoxy-4’-hydroxyphenyl)-1,4-pentadiene-3-on (EHP) has been prepared by aldol condensation from ethyl vanilin and acetone in the presence of hydrocloride acid as a catalyst with 86% yield and melting point 106.4-108.3ºC. Comparation of compound EHP has been determined by UV-VIS, TLC, FT-IR, GC-MS, and NMR. For comparation purposes, the elucidation structure of EHP by chemoffice was of trained. The antioxidant activity of EHP were measured using DPPH method (1,1-diphenyl-2-picryllhidrazil).The antioxidant activity of EHP (IC50 8.66 µg/ml) is lower than the curcumin (IC50 11.44 µg/ml), and GVT-0 (IC50 10.15 µg/ml). Antioxidant activity EHP is better than Curcumin.rnrn(F) Reference : 24 pieces (1988-2007)rnrn(G) Dra. Esti Mumpuni, M.Si., Apt.rn

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Judul Seri

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No. Panggil

KF 892

Penerbit

Jakarta : FFUP., 2008

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Bahasa

Indonesia

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Subjek

Bidara arab, Kuersetin, Pengisi, Granul Instan

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