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ASOSIASI PROTEIN BAX DAN APOPTOSIS SEDIAAN MIKROSKOPISrnHASIL BIOPSI PENDERITA KANKER SERVIKS DI RUMAH SAKIT CIPTO MANGUNKUSUMO DAN HASAN SADIKIN

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ABSTRACTrn(A) HANUM PRAMITA SARI (2009210083)rn(B) ASSOCIATION BAX PROTEIN AND APOPTOSIS OF MICROSCOPICrnSLIDES FROM CERVICAL CARCINOMA PATIENTS BIOPSY INrnCIPTO MANGUNKUSUMO DAN HASAN SADIKIN HOSPITALSrn(C) viii + 66 pages; 4 tables ; 10 pictures ; 13 attachmentsrn(D) Keywords: apoptosis, protein Bax, cervical cancerrn(F) Bax protein playing a central role in cervical cancer development by inducingrnapoptosis in intrinsic pathway. In this study the apoptotic index was measuredrnand the level of existence Bax protein was grouped from pretreatmentrnmicroscopic biopsy specimens from 21 patients with carcinoma cervix stagernIIB-IIIB who had treated chemoradiotherapy in RSCM (10 patients) and RSHSrn(11 patients) between 2010-2011. The specimens were stained byrnimmunohistochemistry method using anti-Bax for protein Bax, kit caspase-3rnfor apoptosis, dan the control negative was made. Apoptosis was grouped byrnapoptotic index. The level of existence Bax protein was grouped by intensity ofrnbrown colour. In this study were obtained 71% (15 cases) showed “low”rnapoptosis (apoptosis index

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No. Panggil

FM 1430

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Jakarta : PERPUSTAKAAN FF UP., 2013

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Indonesia

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NONE

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