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Microencapsulated Kandis Bark Extract (Garcinia Cowa Roxb.) Using Spray Drying Method as Antioxidant

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Kandis bark (Garcinia cowa Roxb.) contains α-mangostin compounds of the
xanthone group which have activity as antioxidants. The purpose of this study
was to produce microcapsules from candis bark extract as antioxidants by using
spray drying method and evaluating the microcapsules formed. Extraction is
carried out using natural deep eutectic solvent (NADES) as an environmentally
friendly alternative to conventional organic solvents that are toxic and harmful
to the environment. The extraction was carried out by ultrasonic assested
extraction (UAE) method. Formulated in 6 formulas with a ratio of ethyl
cellulose coating polymers and solvents used, namely 1: 1 (formulas 1 and 4),
1: 2 (formulas 2 and 5), 1: 3 (formulas 3 and 6) for the solvent used, namely
acetone used for formulas 1, 2, and 3 while for acetone ethanol banding with a
ratio of 1: 2 used for formulas 4, 5, and 6. Microcapsule evaluation tests,
determination of α-mangostin levels and antioxidant activity tests with DPPH
damping were carried out. Based on the results of the study obtained, candis
bark extract has a very strong antioxidant activity of 22.14±0,4524 bpj and for
the results of physical quality examination of microcapsules, candis bark
extract has a brown to light brown color. The morphology is not spherical with
a process yield of 71.78-92.34%. The particle size with an average of 5.3707.326
μm,
has
a
moist
content
of
5.10-9.31%
with
an
absorption
efficiency
of

99,79-99,84%.
Based
on
the
test
results
of
α-mangostin
levels,
and
antioxidant

activity,
the
best
results
were
obtained
in
formula
6

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

TF 1663

Penerbit

Jakarta : Fakultas Farmasi Universitas Pancasila., 2023

Deskripsi Fisik

142 p.

Bahasa

Indonesia

ISBN/ISSN

2019210093

Klasifikasi

NONE

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

-

Subjek

Garcinia cowa Roxb, Natural Deep Eutectic Solvent,

Info Detail Spesifik

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Pernyataan Tanggungjawab

-

Versi lain/terkait

Lampiran Berkas

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