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Development of Optical Methods for Real-Time Whole-Brain Functional Imaging of Zebrafish Neuronal Activity

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Each one of us in his life has, at least once, smelled the scent of roses, read one canto of Dante’s Commedia or listened to the sound of the sea from a shell. All of this is possible thanks to the astonishing capabilities of an organ, such as the brain, that allows us to collect and organize perceptions coming from sensory organs and to produce behavioural responses accordingly. Studying an operating brain in a non-invasive way is extremely difficult in mammals, and particularly in humans. In the last decade, a small teleost fish, zebrafish (Danio rerio), has been making its way into the field of neurosciences. The brain of a larval zebrafish is made up of 'only' 100000 neurons and it’s completely transparent, making it possible to optically access it. Here, taking advantage of the best of currently available technology, we devised optical solutions to investigate the dynamics of neuronal activity throughout the entire brain of zebrafish larvae.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

621.36 LAP d

Penerbit

none : none., 2020

Deskripsi Fisik

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Bahasa

English

ISBN/ISSN

26128039

Klasifikasi

621.36

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

Zebrafish Neuronal Activity
calcium imaging, light-sheet microscopy
epilepsy, behaviour

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

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